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Abstract

HIGH PERFORMANCE LIQUID CHROMATOGRAPHIC METHOD FOR DETERMINATION OF MOMETASONE FUROATE IN HUMAN PLASMA

Mr.Chetan Javsen*, Dr. Y.A. Deshmukh and Dr.Raman Yadav

ABSTRACT

A novel sensitive high-performance liquid chromatography assay is developed and validated for the determination of mometasone furoate in human plasma. This method used a C18 column with a mobile phase consisting of methano: water (88 % :12% ), flow rate is 1 ml/min and UV detection at 248 nm. The method was found to be selective, simple, economical, accurate, reproducible, rapid and reliable for estimation of mometasone furoate level in human plasma.

Keywords: mometasone furoate, human plasma, HPLC.


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