WJPPS Citation

Login

Search

News & Updation

  • Updated Version
  • WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript
  • Call for Paper
    • WJPPS  Invited to submit your valuable manuscripts for Coming Issue.
  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.
  •  
  • New Impact Factor
  • WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

  • WJPPS: MARCH ISSUE PUBLISHED
  • March Issue has been successfully launched on 1 March 2024.

  • ICV
  • WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

  • Scope Indexed
  • WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

Abstract

STUDIES ON THE EFFECT OF OXIDATIVE STRESS INDUCED BY CHLORPYRIFOS ON ANTIOXIDANT HEPATIC ENZYMES IN RAT

Kanika Aggarwal, Devinder Singh*, S. K. Singla

ABSTRACT

Chlorpyrifos (CPF) is an extensively used organophosphate insecticide for crop protection against pests and also in various public health operations. Many studies reported that enzymatic and non-enzymatic antioxidant may play protective role against CPF induced toxicity in mammals. The aim of present study was to investigate the effect of different doses of CPF on antioxidant enzymes. Male rats were divided into 4 groups; Group I (Control received corn oil); Group II (10 mg CPF/kg b. wt./day); Group III (20 mg CPF/kg b. wt./day) and Group IV (30 mg CPF /kg b. wt./day). Animals were treated for 28 days and then their liver tissue was studied for oxidative stress enzymes. CPF toxicity resulted into significant decrease in the activities of SOD, CATALASE and GR in liver tissue.

Keywords: Chlorpyrifos, SOD, Catalase, GR, Oxidative stress, Antioxidants


[Download Article]     [Download Certifiate]

Call for Paper

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Online Submission

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Email & SMS Alert

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More