Abstract

EXTRACTION, ESTIMATION AND THIN LAYER CHROMATOGRAPHY OF FLAVONOIDS: A REVIEW

*Amit Gangwal

Smriti College of Pharmaceutical Education, Indore (M.P.) 452010, India.

ABSTRACT

Since time immemorial flavonoids are in use in various parts of the world for sure shot treatment or for approximate and rudimentary treatment of various ailments. They were among the earliest chemicals isolated in pure form from natural sources. Till date they are the most fancied natural chemical for scientist of various backgrounds (botanist, biochemist, pharmacognosist, pharmacologist, natural product chemist etc), because they are one of the most potent and promising bioactive chemicals, obtained from natural sources. Various flavonoids have been reported in literature for range of pharmacological activities. Worldwide drug discovery is going through a rough patch. Various models are being discussed, new approaches are emerging, and synthetic drugs are enjoying good position among available options, still natural sources can never be undermined, as most of the established drug molecules trace their route to natural sources directly or indirectly. In this review article an attempt has been made to compile basic and crucial information (extraction methods, thin layer chromatography and estimation) on putative secondary metabolite; flavonoids. Compiled information is just and highly concised and widely reported.

Keywords: Flavonoids, extraction, estimation, TLC, drug discovery, natural products.