Abstract

SYNTHESIS AND EVALUATION OF 2-SUBSTITUTED BENZIMIDAZOLES

B.chinnappadu*, S.shirish chandra, V. Sai Prasanna, P.veeranjaneyulu, M.sumanth

ABSTRACT

The wide range of biodynamic properties shown by Substituted benzimidazoles prompted to synthesise using o-phenylene diamine and derivatives of carboxylic acids, inhope of getting potent dynamic agents .In the present study the title Compound was prepared from ophenylene diamine and carboxylic acid derivatives were choosen for synthesis and pharmacological evaluation. The scheme of general methodology for preparation of 2-substituted benzimidazoloes derivatives , method of establishing their identity by means structural conformations by IR, NMR, Mass spectral studies are described in experimental section and spectral studies.

Keywords: o-phenylene diamine, benzimidazoles etc.