Abstract

SYNTHESIS AND PHYSICO-CHEMICAL STUDIES ON (Z)-2-((6-BROMO-2-HYDROXYQUINOLIN-3-YL) METHYLENEAMINO)-5-IODOBENZOIC ACID AND THEIR METAL (II) COMPLEXES

K. Siddappa* and Mallikarjun Kote

ABSTRACT

The Cu(II), Co(II), Ni(II), Zn(II), Cd(II), Hg(II), Mn(II) and Fe(III) complexes of Schiff base (Z)-2-((6-bromo-2-hydroxyquinolin-3-yl)methyleneamino)-5-iodobenzoic acid has been synthesized and characterized by various spectral techniques. The complexes were prepared by reacting the ligand and metal chloride of Cu(II), Co(II), Ni(II), Zn(II), Cd(II), Hg(II), Mn(II) and Fe(III) in ethanol to get a series of mononuclear complexes. The complexes were characterized by CHN analysis, conductivity measurements, magnetic susceptibility, IR, 1H NMR, ESR, UV-Vis and X-ray powder diffraction studies. By these spectral studies it is found that Cu (II), Co (II), Ni (II), Mn(II) and Fe(III) complexes have exhibited octahedral geometry and Zn(II), Cd(II), Hg(II) complexes have exhibited tetrahedral geometry. The ligand and its metal complexes have been screened for their antimicrobial activities. The prepared ligand shows low activity and its metal complexes shows moderate to good activity.

Keywords: 2-amino-5-iodo-bezoic acid, quinoline, Schiff base, Metal complexes and Spectral studies.