Abstract

A REVIEW FUNGAL ENDOPHYTES: AS A STORE HOUSE OF BIOACTIVE COMPOUND.

Akanksha Bhardwaj, Pavan Agrawal*

ABSTRACT

This review describes information that endophytic fungi are the store house of naturally occurring bioactive compound. Plants have been exploited for human benefits for over thousands of years and have been the storage house of compounds for medicine. Endophytic fungi are a kind of fungi that colonize and reside in living and internal tissues of plants without causing any disease to the plant and reproduce by vegetative and sexual methods. Endophytes constitute a large diversity of microbial adaptations that have developed in special and hidden environments. Because of their huge diversity and particular habituation, they can provide a good area for research in the field of making new medicines and novel drug like molecules. Many microorganisms have developed resistance against the current drugs so it is necessary to search for new drugs. In order to provide aid and comfort in all aspects of mankind’s life it is very important to make drugs which have safe bioactive compounds which are not dangerous for human health. There are many challenges in front of scientists for instance rise of new diseases, emergence of virus which are life threatening and management of complications occur after operation in patient with organ transplantation. This has led scientists to hunt for different natural sources that are safe and potent to meet the challenges of twenty first century. Endophytes possess different types of bioactivity, such as antibacterial, antiviral, anticancer and antifungul agents.

Keywords: Endophytes, Bioactive Compounds, Antimicrobial Compounds, Secondary metabolites.