WJPPS Citation

Login

Search

News & Updation

  • Updated Version
  • WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript
  • Call for Paper
    • WJPPS  Invited to submit your valuable manuscripts for Coming Issue.
  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.
  •  
  • New Impact Factor
  • WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

  • WJPPS: MARCH ISSUE PUBLISHED
  • March Issue has been successfully launched on 1 March 2024.

  • ICV
  • WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

  • Scope Indexed
  • WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

Abstract

COMPARATIVE IN VITRO EVALUATION OF COMMERCIAL ACECLOFENAC TABLETS

Mrs. Manali. M. Bhide*, Mr. Sachin. A. Nitave

ABSTRACT

Aceclofenac (ACL), is a synthetic new NSAID, which has been widely used in treatment of rheumatoid arthritis, osteoarthritis and ankylosing spondylitis with minimum side effects. Since Aceclofenac tablet is not an official product of I. P. and practically insoluble in water, it was thought necessary to carryout in vitro testing of the commercial products with special attention to dissolution rate studies. Three different brands (A, B & c) of Aceclofenac tablets 100 mg manufactured in India were evaluated for nine in vitro parameters, both official and non-official, viz., uniformity of weight, dimensions, hardness test, friability test, disintegration test, dissolution test and assay. The dissolution test was carried out in phosphate buffer pH 7.5. The study on dissolution profile revealed that product A had faster dissolution rate while product C has slowest dissolution rate. All the products met the requirements as per general specifications of Indian pharmacopoeia for tablet formulation. Assay value lies within the limit of 90% to 110%.

Keywords: Aceclofenac, Evaluation, Dissolution rate, friability, Assay etc.


[Download Article]     [Download Certifiate]

Call for Paper

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Online Submission

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Email & SMS Alert

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More