Abstract

STUDIES ON ANTIMICROBIAL COMPOUNDS ISOLATED FROM MANGROVE ENDOPHYTIC FUNGI

Alaganandham Elavarasi, Samuel Peninal, Gananaparkasam Sathiya Rathna and Murugaiyan Kalaiselvam*

ABSTRACT

Endophytic fungi were isolated from mangrove leaves of Rhizophora annamalayana in Vellar estuary along southeast coast of India. Isolated colonies were identified and screened for antimicrobial activity. The crude extracts exhibited strong and moderate activity against human pathogens. Maximum zone of inhibition was observed in Fusarium sp. followed by Penicillium sp., Alternaria sp., Nigrospora sp., Rhizopus sp. Potential strain of Fusarium sp was analyzed by GC-MS and two major compounds such as 5-Eicosene, (E) - and 1Dodecanol, 2-methyl (S) were identified. F.moniliforme. was sequenced and it was submitted in NCBI with the Accession number JN681281.These results indicate that endophytic fungi from mangrove leaves acts as potential source of antimicrobial compounds

Keywords: Antimicrobial compounds, Endophytic fungi, F. moniliforme, Mangrove.