Abstract

COMPARISION OF EFFECT OF NEBULIZATION WITH DIFFERENT COMBINATIONS OF MEDICATIONS IN PEDIATRIC PATIENTS WITH WALRI

K. Blessy lavanya*, T.Lakshmi vasundhara, Syed Zahed pasha, Mr.G.Veeramani, Dr. S. Chidambaranathan

ABSTRACT

AIM: To investigate which of the combination of nebulisation is better when compared to each other in management of WALRI in pediatric patients. METHODOLOGY: This study is conducted for a period of 6months (November 2012 to April 2013) in RMMCH a 1600 bedded tertiary care multispecialty hospital situated in southern India. A total of 65 patients in age group of new born to 12 years are enrolled of these 16 (GROUP A) received Ipratropiumbromide+ Salbutamol+ Budesonide, 13 (GROUP B) received Levosalbutamol sulphate+ Budesonide, 13 (GROUP C) received Ipratropiumbromide+ Salbutamol + Ambroxlo+ Hypertonic solution, 23 (GROUP D) received Ipratropiumbromide+Salbutamol+Budesonide+Ambroxol . The respiratory rate, heart rate, overall clinical conditions(using YALES observation scale), RDAI score were measured before 30 minutes and after 20 minutes of nebulization. Results: Both Group A and Group C shows significant improvement in overall RDAI score whereas Gropu A (Ipratropiumbromide+Salbutamol+Budesonide) shows better improvement in heart rate, respiratory rate, and other clinical conditions. Conclusion: Ipratropiumbromide+Salbutamol+Budesonide is the most effective combination for the treatment of WALRI in pediatric patients.

Keywords: WALRI (wheeze associated lower respiratory tract infection), Nebulization, pediatrics