ANTI MICROBIAL EVALUATION OF NEW OXADIAZOLE DERIVATIVES
Chilumula Nageshwar Rao*, K.Blessi Priyanka, J.Ravi, G.Dayakar*
ABSTRACT
5-(2-(2-(arylideneamino) oxazol-5-ylamino) benzoxazol-5-yl)-3-
((dialkylamino) methyl)-1, 3, 4-oxadiazol-2(3H)-thiones (XI)
derivatives were evaluated for antimicrobial activity by using disc
fusion method.The synthesized derivatives were evaluated for
antibacterial activity and antifungal by using Ampicillin sodium and
Clotrimoxazole as a standards. Among all compound XIa, XIb and XIh
are more effective against bacteria. Among the series compound XIb is
exhibited more inhibition against A.niger and C.albicans.
Keywords: Bezoxazole, Oxadiazole, antimicrobial, antifungal, antibacterial.
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