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Abstract

SILICA GEL SUPPORTED BISMUTH TRICHLORIDE CATALYZED ONE-POT SYNTHESIS OF SUBSTITUTED OXAZOLES FROM PROPARGYLIC ACETATES AND AMIDES UNDER MICROWAVE IRRADIATION

A. Thirupathaiah*, Siddhartha Marupati, S. Ramanna and G. Venkateswar Rao

ABSTRACT

A rapid and efficient procedure under microwave irradiation, using silica gel-supported reagents for the synthesis of substitued oxazoles has been developed through bismuth trichloride catalyzed propargylation/cycloisomerization tandem reaction of propargylic acetates and amides.

Keywords: Bismuth trichloride, oxazole, microwave irradiation.


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