TO INVESTIGATE THE HOLD TIME STUDY OF ABACAVIR SULFATE TABLETS 300MG PREPACKAGED IN QUARANTINE AREA
Deepak P Pawar*, Dr. Prashant B Shamkuwar, Sheetal S Chavan
ABSTRACT
To validate the holding time of Abacavir sulfate tablets 300 mg
prepackaged in quarantine area under the prevailing conditions.
Abacavir Sulfate tablets 300 mg were subjected to hold time study at
Initial, 30th, 60th and 90th days. The stored coated tablets were
evaluated for the intact drug in the formula, and compatibility of the
drug with the formulated excipient analyzed to determine the content
uniformity (%) and other parameters which were compared with the
pharmacopoeia limits. After storage of those coated tablets at different
time intervals i.e. at Initial, 30th, 60th and 90th days it was ensured
that the holding time of Abacavir sulfate tablets 300 mg prepackaged in quarantine area is
within the limits of acceptance criteria. From the data it is concluded that the coated tablets of
Abacavir Sulfate tablets 300 mg should be stored upto 90th day. Therefore, extremely
accurate hold-time data were obtained. In light of this data the correct trends in hold-time
study as a function of storage period for Abacavir Sulfate tablets 300 mg coated tablets can
be established.
Keywords: Abacavir Sulfate tablets 300 mg; Content Uniformity; Pharmacopoeia limits.
[Download Article]
[Download Certifiate]