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Abstract

EFFICACY OF CEPHALANDRA INDICA MOTHER TINCTURE IN THE CONTROLLING OF BLOOD SUGAR IN THE MALE ALBINO RAT

Subasri Muthuviveganandavel, Muthuviveganandavel Veerappan,*Muthuraman Pandurangan

ABSTRACT

The aim of this study was to assess the effect of Cephalandra indica (MT) on male albino rat. The effect was assessed on the basis of the results of acute toxicity tests and on the comparison of the results of blood serum biochemical examinations of control and experimental groups. Group-I: sham control, group-II: Placebo control (40% ethanol), group-III: sham control with MT for 3 h and group-IV: sham control with MT for 6hrs were used in the study. Cephalandra indica (MT) oral administered male rats showed changes of blood serum protein, glucose, cholesterol and triglycerides content. Investigations carried out using male albino rats weighing about 125 - 150gms were administered with 1000μl/kg body weight of Cephalandra indica (MT) for group-III: Sham control with MT 3hrs and for group-IV: Sham control with MT 6hrs. At the end of the experimental period, the animals were anesthetized with diethyl ether and sacrificed by cervical decapitation. Blood was collected through cardiac puncture and stored in without EDTA containers, also used for serum biochemical analysis. Cephalandra indica (MT) effect produced decreased amount of blood serum protein, glucose and cholesterol amounts compared with controls. Changes of the serum biochemical compounds leads to positive effect in the different organs cell metabolism.

Keywords: Rats; blood glucose; Cephalandra indica;protein.


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