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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

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WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

WJPPS: APRIL ISSUE PUBLISHED

April Issue has been successfully launched on 1 April 2024.

Abstract

PRELIMEINARY PHYTOCHEMICAL SCREENING AND HEPATOPROTECTIVE ACTIVITY OF METHANOLIC LEAVES EXTRACT OF CYPERUS ROTUNDUS IN CCL4 INDUCED HEPETOTOXICITY IN ALBINO WISTAR RATS

Y.Narasimha Rao* , M.Prasada Rao,V.Rajeswara Rao, K.Suresh, Sk.MohammadRafi, T.Anka Rao, K.Govinda Raju, K.Raja Ram Ambedkar

ABSTRACT

The methanolic extract of leaves of cyperus rotundus at the dose of 200mg/kg body weight per oral was studied for the hepatoprotective effect using Carbontetrachloride induced liver damage in wistar albino rats. Methanolic extract showed significant (p<0.05) hepatoprotective effect by lowering the serum levels of various biochemical parameters such as serum glutamic xaloacetate transaminase (SGOT), serum glutamic pyruvates transaminase (SGPT), alkaline phospatase (ALP), the overall experimental results suggests that the biologically active phytoconstituents such as flavonoids, alkaloids present in the methanolic extract of plant cyperus rotundus may be responsible for the significant hepatoprotective activity and the results justify the use of cyperus rotundus as a hepatoprotective agent.

Keywords: Cyperus rotundus, Hepatoprotective activity Methanolic Extract, carbontetrachloride.

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