Abstract

NASAL DOSAGE FORMS AND DEVICES FOR INTRANASAL DRUG DELIVERY

Sumedh Moharil*, Kamlesh Niranjane, Latika Nasare, Anuradha nagdevte,Nitin Bhople.

ABSTRACT

Intranasal delivery devices deliver medications directly to the nasal cavity , where they can be absorbed directly by the appropriate tissues. Studies have demonstrated that medications against some CNS disorders can be more efficacious when delivered by the intranasal route, particularly if these are the routes of infection. In addition, many drugs may be delivered by intranasal routes. Advantages of these routes of delivery include targeting the drug to the site of infection or disease, rapid absorption into the blood stream, and easier, needle-free delivery. Nasal delivery has a number of compelling advantages over other routes of administration; namely its non-invasiveness, rapid attainment of therapeutically relevant concentrations to the bloodstream, no first-pass metabolism, and ease of administration. Viable nasal delivery technologies have the potential to enable drug developers in creating innovative medicines using already approved products by delivering them through new routes of administration.

Keywords: Nasal dosage form, Nasal devices.