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  • WJPPS APRIL ISSUE PUBLISHED
  • APRIL 2019 Issue has been successfully launched on 1 April 2019

  • WJPPS Impact Factor
  • Its our Pleasure to Inform you that WJPPS Impact Factor has been increased from 6.647 to 7.421 due to high quality Publication at International Level

  • ICV
  • WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

  • Call for Paper
    • WJPPS  Invited to submit your valuable manuscripts for Coming Issue.
  • Updated Version
  • WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript
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Abstract

ZINC IODIDE: A MILD AND EFFICIENT CATALYST FOR ONE-POT MULTICOMPONENT SYNTHESIS OF 3-INDOLE DERIVATIVES AND STUDY OF ITS IN-VITRO ANTI-INFLAMMATORY ACTIVITY

Rohit R. Wakodkar, Pravin Kulkarni, Mazahar Farooqui, and Deepak D. Kayande*

ABSTRACT

An efficient and economical method was developed for the synthesis of 3-substituted indole zinc iodide catalysed condensation between aldehyde, malnonitrile and indole. The process was carried out in ethanol at refluxing temperature. This protocol provides broad applications due to its operation simplicity, shorter reaction time and low cost.

Keywords: Zinc iodide, indole, Multicomponent reactions, aldehyde, anti-inflammatory (in-vitro).


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