Abstract

NEW DEVELOPMENTS IN THE CONTROL OF DENTAL INFECTIONS: REVIEW

Katiyar Aviral*, Prajapati S.K., Kumar Neeraj, Akhtar Ali

Instittute of pharmacy Bundelkhand University, Jhansi (U.P), India

ABSTRACT

Controlled local delivery of antibiotics has been shown to reduce periodontal micro-organisms with minimal side-effects. Controlled drug delivery refers specially to the precise control of the rate by which a particular drug dosage is released from a delivery system with out the need for frequent administration1. The attractiveness of mucosal-targeted controlled drug delivery of active pharmaceutical ingredients (APIs), has led formulation scientists to engineer numerous polymeric systems for such tasks.Polymers has enormous potential for the delivery of therapeutic macromolecules.This article reviews various types of delivery systems evaluated in practical periodontal therapy. Despite the large number of studies showing an enhanced effectiveness of local antibiotherapy.This review highlights the physiological challenges as well as the advances and opportunities for buccal drugdelivery.Particular attention is given to new approaches which can extend dosage form retention time or can be engineered to deliver complex molecules.

Keywords: periodontal,antibiotherapy,buccal drug delivery.