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Abstract

STUDY OF CO-EFFECT OF HELICOBACTER PYLORI ON PREGNANT WOMEN INFECTED WITH CYTOMEGALOVIRUS

Abbas A. A.* and Ramadan A. Doaa

ABSTRACT

Background Human cytomegalovirus (CMV) is a member of the herpesvirus family. Though CMV may found in many organs, cytopathogenicity observed infrequently and clinical manifestations of CMV in the immunocompetent host are rare some of cases infected with CMV and Helicobacter pylori co-infection. Material and methods: the total cases were showed (165) pregnant women which IgG positive collected from Al-Azhar Teaching Hospital (Sayed Glal) Cairo, Egypt; CMV was detected of by Enzyme-linked immunosorbent assays (ElISA), and real time polymerase chain reaction (rt-PCR), the relation between CMV and Helicobacter pylori with risk factor (age, time of apportion, number of apportion, number of delivery, life style, Blood transfusion, use of corticosteroids, gynecologic and medical history of abortion, residence and socioeconomic status). Result: Positive of CMV and H. pylori infected pregnant women were 128 samples as (77%), All samples IgG positive (CMV) in serological tests, All samples negative for (TORCH) Toxoplasmosis Rubella and Herpes simplex virus (HSV), when study Co-effect between CMV and H. pylori found significant positive correlation between PCR, age patients, number of abortion, and. While negative correlation between PCR time of abortion, number of delivery, Use of corticosteroids, Blood Transfusion and life style, there was no statistical significant correlation between PCR and Birth Defect.

Keywords: CMV, ElISA, rt-PCR, Virus, Risk factor, Abortion, pregnant women, H. pylori.


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