Abstract

DEVELOPMENT AND EVALUATION OF A GENERIC ANTI - INFLAMMATORY DRUG FORMULATION

*Choubey Pravir, Manavalan R

ABSTRACT

Generic prototype formulation of an anti-inflammatory drug Celecoxib Capsules 400mg was developed and subjected to various evaluation studies such as physico-chemical properties in-process parameters during encapsulation, stability studies, comparative dissolution profile, and bioequivalence studies. The formulation and process parameters are established to be robust, stable and comparable to the reference product based on comparative in-vitro studies. Celecoxib Capsules 400mg formulation is suitable as a generic alternative to the reference drug product (Celebrex Capsules of Pfizer).

Keywords: Generic, Celecoxib Capsules Dissolution profile, Stability.