Photo Gallery

Login

Search

News & Updation

  • WJPPS MARCH ISSUE PUBLISHED
  • MARCH 2019 Issue has been successfully launched on 1 March 2019

  • WJPPS Impact Factor
  • Its our Pleasure to Inform you that WJPPS Impact Factor has been increased from 6.647 to 7.421 due to high quality Publication at International Level

  • ICV
  • WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

  • Call for Paper
    • WJPPS  Invited to submit your valuable manuscripts for Coming Issue.
  • Updated Version
  • WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript
  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.
  •  

Abstract

ENHANCEMENT OF SOLUBULITY OF PROPIOMAZINE BY PELLETIZATION

A. Aroon, B. Jayanthi* and K. Satyanarayana

ABSTRACT

The present search engrossed on the preparation and evaluation of delayed release pellets of Propiomazine using a different grade of polymers like HPMC 5CPS, PEG 6000 as a sustained released polymer. Propiomazine is an antihistamine blocking H1 receptors, it is used to treat both negative and positive symptoms of schizophrenia, acute mania with bipolar disorder, agitation, and psychotic symptoms in dementia. pellets are multiparticulate dosage form which was formed by the agglomeration of fine powdered excipient and drugs together that leads to the formation of small free flowing spherical or semi spherical particles. The result of the pellets were within the limits which indicated good flow potential for the prepared pellets. Drug-loaded pellets exhibited spherical shape with uniform and smooth coating. Based on the result, Trail 8 coating level formulations are suitable for the successful delivery of the drug into the lower part of intestine and colon. From the present work, it can be concluded that the prepared drug delivery system can be used for Propiomazine drug.

Keywords: Propiomazine, pellets.


[Full Text Article]

Call for Paper

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Online Submission

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More

Email & SMS Alert

World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS)
Read More