A STUDY OF VITAMIN D LEVELS IN PATIENTS OF CORONARY ARTERY DISEASE
Dr. Nitin Tyagi*, Aroop Mohanty, Charanjeet Kaur, Ankita Kabi, Supriti Kumari, Mamta, Sugandha Sharma, Sunita Rani, Dhananjay Kumar Sahu, Jagdish Prasad,
Bhaskar Charana Kabi
ABSTRACT
Background: Coronary Artery Disease (CAD) is a major global health
problem. Recent studies demonstrated that lower vitamin D level
(<30ng/ml) is associated with higher blood pressure and directly or
indirectly with CAD, due to vascular endothelial damage. However the
results are inconsistent. Aims and objectives: To find the association
between 25(OH) vitamin D serum levels and coronary artery disease
risk. Materials and Methods: In this case control study, we compared
Vitamin D levels in 120 subjects with angiographically proven
coronary artery disease with those of 120 age and sex matched healthy
controls. Serum 25(OH) vitamin D levels were estimated by ELISA.
Data was collected and analysed by suitable statistical methods.
Result: Levels of 25(OH) vitamin D were 11.7±1.06 ng/ml in cases as
compared to 24.3±1.54 ng/ml in controls (p value <0.0001).
Conclusion: There is a strong inverse association between 25(OH) vitamin D serum levels
and coronary artery disease risk.
Keywords: Vitamin D, coronary artery disease.
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