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Abstract

DETECTION THE ROLE OF SOME INFLAMMATORY MARKERS IN PATIENT WITH ACUTE AND CHRONIC TONSILLITIS

Aysha W. Abd ALaziz*, Sahlah K. H. Abbas and Salah S. Zain Alabedin

ABSTRACT

This study was designed to evaluate the hematological and some immunological parameters in patients with acute and chronic tonsillitis. swabs were obtained from the tonsils of 100 patients with acute and chronic tonsillitis to detect streptococcus pyogenes and staphylococcus aureus. and blood samples collected to detect the immune parameters in the patient's serum. The results of culture showed that 18 samples (11.92%) were positive to strep. pyogenes while 29 samples (19.21%) were positive to staph. Aureus. A complete blood count showed statistically significant changes in the presence of tonsillitis. Serological test showed significantly increased in the complement protein C3, C4 and IgA level In acute and chronic tonsillitis. Serum level of IL-10 and TNF-α showed statistically difference due to its multiple functions, including cellular regulatory function and influence in many diseases, including tonsillitis.

Keywords: Acute tonsillitis, Chronic tonsillitis, IL-10, TNF- ?, Complement, IgA.


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