Abstract

A PROSPECTIVE OBSERVATIONAL STUDY ON PREVALENCE OF CHRONIC KIDNEY DISEASE IN DIABETES MELLITUS

Muthe Mounasree*, Masani Vara Lakshmi, Maredupaka Bhavana, Shaik Saaduddin, Dr. Zainab Begum, Dr. A. Srinivasa Rao

ABSTRACT

Background: Diabetes is a metabolic disorder that results from deficiency in insulin production and insulin resistance. Chronic Kidney Disease is defined as kidney damage or glomerular filtration rate (GFR) <60 mL/min/1.73 m2 for 3 months or more. In 2013, diabetes led to more than 51,000 new cases of kidney failure and over 247,000 people are currently living with kidney failure resulting from diabetes.[1] Methodology: This study was conducted with the aim to assess the percentage of population at risk of Chronic Kidney Disease in Diabetes Mellitus, to determine the stages of Chronic Kidney Disease and to assess the quality of life of the patient that who are diagnosed with Chronic Kidney Disease in Diabetes in Mallareddy Narayana Multispeciality Hospital, Suraram, Hyderabad. This study is prospective observational in nature and the subjects enrolled in this study were about 200. Informed consent was obtained from all the subjects. The stages of Chronic Kidney Disease were determined using eGFR value by CKD-EPI equation.[9] The quality of life of subjects were assessed by using SF-36 HS scale.[2] Results: This study identifies the percentage of population at risk of chronic kidney disease in Diabetes, stages of Chronic Kidney Disease and quality of life of subjects. A total of 200 diabetes patients were observed among them 77 subjects (37.99%) were with Chronic Kidney Disease, of which stage-5 (End Stage Renal Disease) was prominent. 24.53% of subjects were under dialysis. Quality Of Life is categorized into 9 activities, out of which role limitations due to physical health is more effected with a percentage of 22.5%. Conclusion: The percentage of population at risk of chronic kidney disease in diabetes was found to be 37.99%. Out of which, stage-5 Chronic Kidney Disease was more prominent and are under dialysis.

Keywords: Diabetes mellitus, Chronic Kidney Disease, serum creatinine, Estimated Glomerular Filteration Rate, Quality Of Life, End Stage Renal Disease.