Abstract

PHYTOCHEMICAL SCREENING AND ANTIMICROBIAL ACTIVITY OF POLYHERBAL AYURVEDIC FORMULATION; PATOLADI KVATHA CHURNA FOR SKIN DISEASES

Senthamil Kavitha M.*, Radha R., Vadivu R. and Nartunai G.

ABSTRACT

The antibacterial and antifungal activity of the ethanol extract from the Patoladi kvatha churna was studied using disc diffusion and well diffusion method against Escherichia coli, Proteus vulgaris, Klebsiella pneumoniae, Pseudomonas aeruginosa, and Candida albicans. Phytochemical screening of the Patoladi kvatha churna revealed the presence of some bioactive components, which have been linked to antimicrobial properties. Various chemical tests and TLC, HPTLC, GC-MS studies showed the presence of flavonoids, alkaloids, glycosides, sterols and phenolic compounds when tested on ethanolic extract of Patoladi kvatha churna. Results suggest that the ethanolic extract has significant antibacterial & antifungal activity against tested bacteria. The Present study justifies the claimed uses of Patoladi kvatha churna in the traditional system of medicine to treat various skin diseases.

Keywords: Antimicrobial activity, Patoladi kvatha churna, Phytochemical screening, Inhibition zones.