Abstract

TRANSDERMAL DRUG DELIVERY SYSTEM: A REVIEW

Verma Sushma and Ojha Abhishek*

ABSTRACT

Skin is considered as the largest organ of the body and it has many different functions. The skin functions occur in thermoregulation, protection, metabolic functions and sensation. The skin is divided into two main regions, the epidermis, and the dermis, one of each providing a distinct overall role function of the skin. The dermis is mainly attached to an underlying hypodermis, which is also called subcutaneous connective tissue, which generally stores adipose tissue and also recognized as the superficial fascia of gross anatomy. Basically it is composed of three layers. The outer-most layer is called the epidermis, which serves as a barrier and protects the body from any infection. The second layer is called the dermis and consists of connective tissues which cushion the body from stress and strain. Now a day‟s the transdermal drug delivery system is the most prominent method for the drug delivery. Transdermal drug delivery system is basically the topically administered drug which are generally in the form of patches for the controlled and pre-determined effects of drug. These devices allow the drug to be delivered through the skin barrier or the outer most layer of the skin. Polymers are called backbone for the transdermal drug delivery system.

Keywords: Skin Introduction, Types of skin, transdermal drug delivery system, evaluation.