Abstract

EVALUATION OF ANTIFERTILITY ACTIVITY OF ETHANOLIC EXTRACT OF Ixora coccinea Linn. BARK IN FEMALE ALBINO RATS

Laisy Jose*, Sujesh M and Prof. Dr. Jyoti Harindran

ABSTRACT

The plant kingdom is a rich source of biologically active agents, revealing various types of pharmacological activities. India has a rich heritage, use of medicinal plants for contraceptive activities in female as well as in male. The present study on antifertility activity using ethanolic extract of Ixora cocinea bark shows anti-implantation and abortifacient activity in dose dependent manner in female wistar albino rats. The hormone estimation and histological evaluation of the uterus also supports the study result. The phytochemical screening shows presence of flavonoids, steroids etc, The litrature review shows that flavonoids and phytosteroids can influence hormone level in body and fertility in animals and humans. The present work was a preliminary effort to prove the claimed antifertility activity of the plant using various animal models.

Keywords: Abortifacient activity, ant-implantation activity, antifertility activity, Ixora coccinea.