Abstract

PRESCRIBING PATTERN OF ANTIMICROBIALS IN INTENSIVE CARE UNIT OF A TERTIARY CARE HOSPITAL

Dr. R. Kothai*, Dr. B. Arul, Dr. S. R. Rangabhashiyam, Praveena Nair, Reeja. K. Raj and Ruth Rajan

ABSTRACT

Prescription pattern monitoring studies (PPMS) are drug utilization studies with the main focus on prescribing, dispensing and administering of drugs. They promote appropriate use of monitored drugs and reduction of abuse or misuse of monitored drugs. PPMS also guide and support prescribers, dispensers and the general public on the appropriate use of drugs, collaborate and develop a working relationship with other key organizations to achieve a rational use of drugs. This prospective observational study was conducted to assess the prescribing pattern of antimicrobials in the ICU of Vinayaka Missions Kirupananda Variyar Medical College & Hospital (VMKVMCH), Salem. This form of monitoring and evaluation of drug prescribing pattern can suggest necessary modification in prescribing practices. 100 consecutive patients who were admitted to different department ICU during the study period of six months from November 2016 to April 2017 where selected. From 100 consecutive prescription, 60% was reported from MICU, 1-3 days was the highest duration of ICU stay and male gender had high preponderance. Most frequently used AMA's was ceftriaxone and cefotaxime from cephalosporin class. Injections were most preferred dosage form and were frequently administered through IV route. Most AMA prescription was made with bacteriological culture and sensitivity evidence. Prescriptions had AMA's prescribed in combination and DI was frequently reported. There is a need for motivating the physicians to prescribe less number of antimicrobial agents in order to minimize the drug interaction. This can be achieved by periodic evaluation and framing a better prescribing strategy.

Keywords: Antimicrobial Agent, ICU, Prescribing Patterns, Cephalosporin.