Abstract

“FORMULATION AND EVALUATION OF FAST DISSOLVING TABLETS OF LANSOPRAZOLE”

*Seema Farheen, Shaik Zubair, Nuha Rasheed and Abdul Saleem Mohammad

ABSTRACT

Lansoprazole is a proton pump inhibitor used as anti ulcer drug. In the present work, fast dissolving tablet of Lansoprazole was design with a view to and provide a quick onset of action. The main objective of the study was to formulate fast dissolving tablets of Lansoprazole to achieve a better dissolution rate and further improving the bioavailability of the drug. Fast dissolving tablets prepared by direct compression and using super disintegrates in different concentration and evaluation parameters. The prepared tablets were evaluated. Among all, the formulation F5 containing super disintegrate cross povidine and sodium starch glycolate was considered to be best formulation, which release up to 85% in 5 minutes.

Keywords: Lansoprazole, super disintegrates, In-vitro tests.