Abstract

COORDINATION COMPLEXES OF Zn+2, Cu+2, Fe+3 AND THEIR APPLICATIONS IN CELL BIOLOGY (A REVIEW)

*Nazir Ahmad Wani

ABSTRACT

Our desire to understand how the individual molecules that make up cells organize, interact and communicate to form living systems has lead to the burgeoning field of chemical biology, an interfacial area of science that combines aspects of chemistry. The study of matter and its transformations and biology. The study of living things and their interactions with the environment. The defining feature of chemical biology is the use of chemical approaches and small molecules to interrogate or manipulate biology. These small molecules are synthetic or naturally occurring ones that, for example, bind to DNA to affect protein expression levels, bind to proteins to inhibit their function, interact with lipids to alter membrane integrity, or become fluorescent in response to a metabolic event. Because small molecules can affect biochemical function, there is a clear link between chemical biology and pharmacology and medicine.

Keywords: transformations, pharmacology, biochemical function, DNA binding.