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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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Updated Version

WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript

Call for Paper

WJPPS Invited to submit your valuable manuscripts for Coming Issue.

Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

New Impact Factor

WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

Scope Indexed

WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

WJPPS: APRIL ISSUE PUBLISHED

April Issue has been successfully launched on 1 April 2024.

Abstract

EVALUATION OF LAKSHADI GUGGUL ON EXPERIMENTALLY INDUCED GLOBAL CEREBRAL ISCHEMIA/ REPERFUSION INJURY IN RATS

Singh Harmeet* and Nidhi Chaudhary

ABSTRACT

Background: Lakshadi guggul has been used in oriental medicine to treat a variety of remedies, including Osteoporosis. Lakshadi guggul is rich in estrogen potentiazing contents have been identified as major active component exhibiting neurotrophic, anti-apoptotic and neuroprotective effects. Present study is to evaluate Lakshadi guggul on experimentally induced Global Cerebral Ischemia/Reperfusion Injury in rats. Material and methods: Neuroprotective activity was carried out by global cerebral ischemia on swiss albino rat by carotid artery occlusion for 17 min followed by 24 hr reperfusion. Then after 24 hr blood sample was collected by retro orbital route and after that rats were sacrificed by cervical dislocation method, then brain was removed for various biochemical analysis.

Keywords: Estrogen, lipid peroxidation, lactate dehydrogenase, Interlukin-1, Malondialdehyde, Thiobarbituric acid reactive substances.

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