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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

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WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

WJPPS: APRIL ISSUE PUBLISHED

April Issue has been successfully launched on 1 April 2024.

Abstract

SYNTHESIS, ANTIMICROBIAL AND ANTI MYCOBACTERIAL ACTIVITY OF SOME CHALCONE DERIVATIVES OF INDANE-1,3- DIONE.

Siddharth Desai* and Dr. V. Girija Sastry

ABSTRACT

In the continuous study of our research program,initially we synthesized some chalcone derivatives of indane-1,3-dione using conventional method by reacting 2- acetyl indane-1,3- dione(1) with different aromatic aldehydes.For this, compd(1) was obtained by reacting phthalic anhydride with acetic anhydride and acetyl acetone in the presence of triethyl amine. The synthesized compounds(2a-f) have been characterized by TLC, IR and.1H-NMR spectroscopy and evaluated for their antibacterial, antifungal and antitubercular activities.

Keywords: Chalcone, indane-1,3-dione, aromatic aldehydes, antitubercular activity.

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