Abstract

A CRUCIAL ROLE OF GUDUCHI (TINOSPORA CORDIFOLIA) IN NEPHROTIC SYNDROME

Dr. Sadhana Prithviraj Chavan*, Prof. Dr. B. B. Kadlaskar, Dr. Pravin Sawant, Dr. Raosaheb Rathod, Dr. Anuja Hari Gholap, Dr. Hardik K. Modi

ABSTRACT

Nephrotic syndrome is a kidney disorder characterized by proteinuria, hypoalbuminemia, hyperlipidemia and edema. It can affect any age group.Nephrotic syndrome is a comparatively rare but form major manifestation of kidney disease. Nephrotic syndrome has an occurrence of three new cases per 100000 each year in adults. Management of nephrotic syndrome according to modern science varies with different stages of the disease. The purpose of treatment is to relieve symptoms, prevent complications, and delay kidney damage.Patient with primary nephrotic syndrome needs corticosteroids but many times they may have relapse or become steroid dependent or resistant to it. Then alternative agents like cyclophosphamide, cyclosporine, levamisole which may be used in a combination. According to Ayurveda, there are number of drugs which can be used in nephrotic syndrome but Guduchi (Tinospora cordifolia) plays a specific role in nephrotic syndrome. It belongs to family Menispermaceae. Guduchi is said to be one of the best rasayana (adaptogens) in Ayurveda. As per its chemical constituents it has antioxidant property. It augments or diminishes immune response so it act as immunomodulator. It even has a nephroprotective property. Hence it is beneficial when used with modern therapeutic drugs in the treatment of steroid dependent frequent relapsers and steroid resistant patients of nephrotic syndrome.

Keywords: Nephrotic syndrome, Guduchi, Immunomodulator.