Abstract

EVALUATION OF ANTIBACTERIAL POTENTIAL OF DIFFERENT EXTRACTS OF TECTONA GRANDIS

Shyamji Shukla*, Nidhi Mishra, Harshita Shukla and Sardul Singh Sandhu

ABSTRACT

The resistance of pathogenic bacterial strains to antibiotics is the major issue all over the world. Therefore the present investigation was conducted to explore new biological sources for antibacterial activity. The leaves of Tectona grandis were collected and antibacterial activity was examined through agar well diffusion method. Tectona grandis extracts were prepared in Butanol, Methanol, Ethanol, Chloroform and Distill water. The ethanolic extract exhibited maximum and broad spectrum activity against all tested bacterial pathogens viz., S. typhi (22mm), followed by K. pneumoniae (20mm), E.coli (18mm), Streptococcus pyogens (16mm) Enterococcus species (15mm).The methanolic extract showed moderate activity against two bacterial species viz., S.typhi (15 mm) and Streptococcus pyogens (10 mm). On the other hand narrow spectrum activities were recorded in case of butanolic, aqueous and chloroform extracts, which expressed activity against only one bacteria viz., Enterococcus species (10 mm), E.coli (14 mm) and E.coli ( 9 mm) respectively. Thus on the basis of this study it is concluded that ethanol extract has highest antibacterial potential.

Keywords: Tectona grandis, Antibacterial potential, Phytochemical screening, well diffusion.