Abstract

REVIEW ON NANOSPONGES: A NOVEL DRUG DELIVERY

Sharma Nishant*, Kumar S. L. Hari and Aggarwal Geeta

ABSTRACT

Nanosponges have emerged as one of the most promising fields of science because of their perceived application in controlled drug delivery. Effective drug delivery at a targeted site had given the possibility to perform the precise function to control the release rates and have a better compliance on the health care system but the chemistry possessing complex form had made conditions complicated But the invention of nanosponges has given a significant approach toward solving this problem. Nanosponges are tiny sponges having size of about a virus and can be filled with variety of drugs. These tiny sponges can circulate around the body until they encounter the specific target site and stick on the surface and begin to release the drug in a controlled and predictable manner. Some cyclodextrins based nanosponges proposed nanodelivery system and form porous insoluble nanoparticle having crystalline and amorphous nature. Because the drug can be released at the specific target site instead of circulating throughout the body it will be more effective for a particular given dosage. A wide variety of drugs can be loaded into nanosponge for targeting drug delivery. Both lipophilic as well as hydrophilic drugs can be loaded into nanosponges. Nanosponge drug delivery system has emerged as one of the most promising fields in life science.

Keywords: Nanosponges, cyclodextrins.