Abstract

ANTIMICROBIAL ACTIVITY OF ROOT EXTRACTS OF THE MEDICINAL PLANT HEMIDESMUS INDICUS (L.) R. BR. VAR. PUBESCENS (W. & A.) H. K. F.

Sandeep Darbari*, Anurag Agrawal, Poonam Verma, Tuman P. Rai, Rishabh Garg, Sashi Bhushan Chaudhary

ABSTRACT

The medicinal plant i.e. Hemidesmus indicus (L.) R. Br. var. pubescens (W. & A.) H. k. f. was selected for antimicrobial studies. The solvent used for the extraction of plant roots were ethanol and chloroform water. The in vitro antibacterial and antifungal activity were performed by agar well diffusion method. The most susceptible Gram-Positive and Gram-Negative bacteria & Fungi were tested. The extracts of plant Hemidesmus indicus (L.) R. Br. var. pubescens (W. & A.) H k. f. inhibited the growth of the investigated bacterial strains & fungi. The ethanol extract and chloroform water were compared with the standard antibiotics, Ciprofloxacin, Amoxicillin for antibacterial and Amphoteracin, Griseofulvin for antifungal activities. The results obtained in the present study suggests. The present study suggests that the Hemidesmus indicus (L.) R. Br. var. pubescens (W. & A.) H. k. f. could be used in treating diseases caused by the test organisms.

Keywords: Antibacterial activity, Anti fungal activity, Ciprofloxacin, Hemidesmus indicus (L.) R. Br. var. pubescens (W. & A.) H k. f.