Abstract

ORGANOLEPTIC AGENTS: ADAPTABILITY, ACCEPTABILITY AND PALATABILITY IN FORMULATIONS TO MAKE IT LUCRATIVE

Debojyoti Basu and Prof. Dr. Dhrubo Jyoti Sen*

ABSTRACT

Organoleptic agents are one of the important members of pharmaceutical aids. Pharmaceutical aids are the components which have no medicinal value but these are essential to formulate any drug into medicine with lucrative look so that it can be easily acceptable by the patients. Organoleptic additives promote appearance and palatability of pharmaceutical dosage forms. If the product does not have acceptable colour, flavor and taste the patient would try to avoid using it. There is a definite psychologic basis for drug therapy in which the colour, flavor and taste of pharmaceutical preparation can play their own part. Mostly the drugs are of bitter and arid taste which are been prescribed by the physician for oral administration by tablets or syrups. These medications are being avoided by patients through oral route because taste buds don’t welcome these through oral route due to their unpleasant taste. If these dosage forms are being incorporated by organoleptic agents to improve their colour, flavour and taste then these are gladly accepted by patients (pediatric and geriatric). Human has sense of organs: eye, ear, nose, throat (ENT). Eye accepts lucrative coloured matters, ear accepts well harmony, nose accepts attractive smell and throat accepts palatable taste from taste buds of tongue. Colourful medicine with acceptable flavour with lucrative taste is always ready to consume by any patient.

Keywords: API (Active Pharmaceutical Ingredient), Drug, Medicine, Formulation, Colour, Flavour, Taste bud, FDA, FD&C, Dyes, Lake Dyes, Mottling, Pitting.