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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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Updated Version

WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript

Call for Paper

WJPPS Invited to submit your valuable manuscripts for Coming Issue.

Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

New Impact Factor

WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

Scope Indexed

WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

WJPPS: APRIL ISSUE PUBLISHED

April Issue has been successfully launched on 1 April 2024.

Abstract

TRAMADOL IN THE MANAGEMENT OF PREMATURE EJACULATION: A PRAGMATIC REVIEW

*Niraj Khatri Sapkota and Kailash Chandra Swain

ABSTRACT

Premature ejaculation (PE) is the most common sexual disorder affecting 20%-30% of adult men; its etiology still remains idiopathic. Tramadol is a synthetic codeine derivative with a weak agonistic activity on the mu- opioid receptor. It is a unique centrally acting analgesic which also inhibits the neuronal reuptake of nor -adrenaline and serotonin. This review is presented to evaluate efficacy, safety, tolerability, addiction liability on-demand dosing tramadol that is effective in lengthening intra vaginal ejaculation latency time (IELT) in men with varying degrees of PE disorder following treatment.

Keywords: Tramadol, analgesic, opioid, IELT, Premature ejaculation.

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