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Abstract

EVALUATION OF ANTI INFLAMMATORY ACTIVITY OF ALCOHOL AND AQUEOUS EXTRACT OF EPIPHYLLUM OXYPETALUM LEAVES

Rucha Dandekar*, Bharti Fegade and Arvind Naik

ABSTRACT

Objective: The main objective of the study is to evaluate the anti inflammatory of alcohol and aqueous extract of Epiphyllum oxypetalum leaves. Methods: The study was carried out by using invitro method which included human red blood cell membrane stabilisation and inhibition of protein denaturation method. The animal study was also carried out in albino wistar rats. Results: The percentage inhibition was seen maximum in 300 μg/ml concentration of alcohol and aqueous extract by using invitro methods where as the percentage inhibition in alcohol and aqueous extract in animal study were found be maximum at 600mg/kg and 200mg/kg respectively. Conclusion: The alcohol extract and aqueous extract of Epiphyllum oxypetalum leaves exhibit anti inflammatory activity.

Keywords: anti inflammatory, Epiphyllum oxypetalum, membrane stabilisation, protein denaturation.


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