Abstract

TO EVALUATE THE ANTI-INFLAMMATORY ACTIVITY OF THE METHANOL EXTRACT OF THE LEAVES OF ABUTILON HIRTUM

N. B. Sridharamurthy* and R. Yogananda , Pruthvi B.P

ABSTRACT

The different experimental models used for the evaluation of anti-inflammatory are Carrageen induced paw edema; Histamine induced paw edema. The methanol extract of the leaf of Abutilon hirtum showed significant decreased inflammation in both the models selected for screening of anti-inflammatory activity. In both the models the p value of the extract II is p< 0.001 and extract I is p<0.01. From the above results it is concluded that the methanol extract of the leaves of Abutilon hirtum confirms the anti-inflammatory activity by its phyto-constituent, biological and histo-pathological observations.

Keywords: Abutilon hirtum, anti-inflammatory activity.