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World Journal of Pharmacy and
Pharmaceutical Sciences

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

Impact Factor : 8.025

ICV : 84.65

WJPPS Citation

	All	Since 2019
Citation	5450	3969
h-index	23	20
i10-index	134	84

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WJPPS introducing updated version of OSTS (online submission and tracking system), which have dedicated control panel for both author and reviewer. Using this control panel author can submit manuscript

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WJPPS Impact Factor has been Increased to 8.025 for Year 2024.

WJPPS Rank with Index Copernicus Value 84.65 due to high reputation at International Level

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WJPPS is indexed in Scope Database based on the recommendation of the Content Selection Committee (CSC).

WJPPS: APRIL ISSUE PUBLISHED

April Issue has been successfully launched on 1 April 2024.

Abstract

UV SPECTROPHOTOMETRIC ESTIMATION OF DILTIAZEM HYDROCHLORIDE IN BULK AND TABLET DOSAGE FORM

Rohan D. Kuntawar*, Sugandha V. Mulgund

ABSTRACT

A simple, precise, accurate and economical spectrophotometric method has been developed for estimation of Diltiazem hydrochloride. The standard and sample solutions were prepared by using distilled water as a solvent. Quantitative determination of the drug was performed at 236 nm. The linearity was established over the concentration range of 6-16 μg/ml for Diltiazem hydrochloride with correlation coefficient value of 0.999. Precision studies showed that % relative standard deviation (%RSD) was within range of acceptable limits (<2). The mean percentage recovery was found to be 104.18%. The proposed method has been validated as per ICH Q2 (R1) guidelines. This method can be used for routine quality control analysis of Diltiazem Hydrochloride in bulk and pharmaceutical formulations.

Keywords: Diltiazem hydrochloride, UV spectrophotometry, Validation

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