Abstract

BISPHENOL A AND ITS EFFECT ON HUMAN HEALTH: A REVIEW

Abdul Rasheed. Md*

ABSTRACT

Bisphenol A (BPA) is an industrial chemical produced in large quantities for use primarily in the production of polycarbonate plastics and epoxy resins, thermal paper, BPA-based products include DVDs, computers, home appliances, spectacles and optical lenses, reusable water bottles, food storage containers, sports safety equipment, medical equipment, construction materials, paints and coatings. BPA contamination may occur from many different sources, but the most common way of BPA contamination is through packaged foods or beverages where the packing material contains BPA human exposure to BPA may arise through BPA leaching from these materials into foods. Over the past few years, considerable scientific evidence indicates that there have been many issues raised all over the world on the use of BPA. BPA is known to possess estrogenic activities; hence, it mimics the role of estrogen once it enters in to living systems. Therefore BPA belongs to a group of chemicals termed “Hormone disruptors” or “Endocrine disruptors”. It can cause damage to reproductive organs, thyroid gland, urino-genital abnormalities in male babies, a decline in semen quality in men, early onset of puberty in girls, metabolic disorders including insulin resistant (type 2) diabetes and obesity, neurobehavioral problems, and most recently it has also been linked to cancer development in human

Keywords: Bisphenol A, BPA-based products, Endocrine disruptors.