Abstract

REVIEW ON NON-IONIC SURFACTANT BASED ORGANOGEL FOR TRANSDERMAL DELIVERY

Varsha Gupta*, Meenu Nagpal, Imran Khan, Geeta Aggarwal, Rupinder Kaur, Sukhdev Singh, Tapan Behl, Upendra Kumar Jain

ABSTRACT

Organogel, a viscoelastic system, can be regarded as a semi-solid preparation. An organogel is a non crystalline, non-glassy thermoreversible (thermoplastic) solid material composed of a liquid organic phase.the three-dimensional networked structure formed due to the physical interactions amongst the self assembled structures of compounds regarded as gelators. In general, organogels are thermodynamically stable in nature and have been explored as matrices for the delivery of bioactive agents. In the current manuscript, attempts have been made to understand the Properties of organogels, various types of organogelator and some applications of the organogels in controlled delivery.

Keywords: Non-ionic surfactant based organogels (NOs), transdermal drug delivery, skin permeation study.