ECO-FRIENDLY PREPARATION AND BIOLOGICAL ASSESMENT OF Cr(III), Mn(II) AND Fe(III) COMPLEXES WITH PHENYLACETYLUREA AND BUTANOATE ION LIGANDS
Arunachalam, A.*, Ramachandramoorthy,T., Padmavathy, S., Narendran, R. andAmala Fathima Rani,S.
ABSTRACT
Phenylacetylurea (PAU) is a biologically active, bidendate neutral
ligand. The present study deals with the microwave assisted
preparation, physico-chemical, spectral and biological
characterization of Cr(III), Mn(II) and Fe(III) complexes containing
PAU and butanoate ion (but) ligands. The molecular formulae of the
complexes were arrived at from the estimation of metals, electrical
conductivities, and effective magnetic moment (μeff) values. The
electronic spectral data indicate the probable geometry of the
complexes. The antibacterial and anti fungal screening of the above
three complexes against the bacteria, viz., Raoultella planticola, Vibrio
cholerae, Lactobacillus brevis, Pseudomonas aeruginosa and Micrococus luteus and fungi,
viz., Candida albicans, Aspergillus oryzae, Aspergillus niger, Aspergillus flavus and
Aspergillus sojae were carried out. The results indicate that the Fe(III) complex exhibits
higher antibacterial activity than Cr(III) and Mn(II) complexes and pure ligands. All the three
complexes show low anti fungal activity than the reference compound, ketokonazole. The
diphenylpicrylhydrazyl (DPPH) free radical scavenging activity of the above three complexes
are lower than the standard compound, vitamin-C.
Keywords: Cr(III), Mn(II) and Fe(III) complexes, Phenylacetylurea, Antibacterial, Anti fungal.
[Download Article]
[Download Certifiate]