COMPARATIVE STUDY OF ANALGESIC ACTIVITY OF TWO INDIAN MEDICINAL PLANTS: JASMINUM SAMBAC & FICUS RECEMOSA L
Dhananjay.B. Deshmukh*, Kuntal G. Padwal & Dushant D. Gaikwad
ABSTRACT
Jasminum sambac & Ficus resemosa linn is an annual plant belonging
to the family Oleaceae & Moraceae respectively found widely
distributed in the region of South & southeast Asia, Europe, Malaysia
and Australia. In folk medicine, the plant is used as tonic, aphrodisiac,
antipyretic, antiseptic, antidiabetic and urinary tract anti-infections.
The present study was undertaken to examine analgesic properties in
the flower & fruit by ethanolic extracts in mice. The analgesic effect of
ethanolic extracts was evaluated by ‘Tail flick method’ and ‘acetic
acid-induced writhing test’ in mice by using Ibuprofen (30 mg/kg) as
reference drugs. Ficus resemosa linn fruit ehanolic extract possess
analgesic activity, but here we also used Jasminum sambac flower extract to check the extent
of difference in activity. In the tail flick method with ethanolic extracts of Ficus resemosa
linn fruit (400 mg/kg), the basal reaction time was increased significantly (p<0.01) and the
percentage increase in threshold to pain was also significant as compared to standard &
Jasminum sambac flower extrac . The ethanolic extract of fruit (400 mg/kg) possessed
significant analgesic activity, as in acetic acid-induced writhing test, the writhing count was
reduced significantly (p<0.01) compared to standard and flower ethanolic extracts.
Keywords: Jasminum sambac, Ficus resemosa linn., analgesic activity, acetic acid-induced writhing test, Tail flick method.
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