Abstract

FLOATING DRUG DELIVERY SYSTEM: A REVIEW

N.R.Sisode*, T.J.Shaikh, R.D.Wagh

ABSTRACT

This is the novel dosage forms that can be retained in the stomach for a prolonged and predictable period of time. One of the most feasible approaches for achieving a prolonged and predictable drug delivery profiles in the gastrointestinal tract is to control the gastric residence time, using gastroretentive dosage forms that will provide us with new and therapeutic options. From the formulation and technological point of view, the floating drug delivery system is considerably easy and rational. The discussion of FDDS extends with in-vivo, in-vitro techniques, the floating and swelling characteristics of several excipients and more relevant modified dissolution method. This work focuses on to the current technological developments with pharmaceutical application of FDDS.

Keywords: Floating drug dlivery system,GIT,Caloric content,Gastroretention,Bioadhesive system,Absorption enhancement.