CONNECTION BETWEEN AGEING AND CANCER
*Ankur Sood
ABSTRACT
The risk of many chronic diseases increases when the peoples get
older. The chronic diseases are increases due to common theories of
ageing, such as mutation accumulation, wear and tear, and antagonistic
pleiotropism etc. However, the risk of some chronic conditions (e.g.
asthma, arterial hypertension) declines in the old. At first glance, it
doesn’t look like that ageing and cancer have any relationship. The
scientists have intrigued the relationship between cancer and ageing for
decades. It has long been widely accepted that ageing is the single
greatest risk factor for developing cancer. Ageing may increase or
decrease the susceptibility of various tissues to initiation of
carcinogenesis and usually facilitates promotion and progression of
carcinogenesis. A number of events at the molecular, cellular, and physiologic levels are
associated with ageing that influence carcinogenesis and subsequent cancer growth. Here we
review the main points to understand the connection between the ageing & cancer.
Keywords: Chronic diseases, ageing, cancer.
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