Abstract

IDENTIFICATION OF POTENTIAL PLANT STEROLS FROM IPOMOEA AQUATICA FORSK FOR ALZHEIMER’S DISEASE BY GC-MS ANALYSIS

D.Sivaraman *, P. Panneerselvam, P.Muralidharan, T.Purushoth Prabhu, R.Vijaya Kumar

ABSTRACT

Ipomoea aquatica Forsk (IA) belongs to the family Convolvulaceae grows wild and is cultivated throughout Southeast Asia and it is a widely consumed vegetable in these regions and also considered to be as an important folklore medicine for the treatment of various ailments. Only a very few scientific studies have been conducted on its medicinal, pharmacological and ethano botanical aspects of this plant. The current study was carried out to analyze the active phytoconstituents present in the leaf of Ipomoea aquatica. Total of eighteen constituents was identified in the gas chromatography with mass spectroscopic analysis of hydro alcoholic extract of Ipomoea aquatica Forsk (HAEIA) .In which the bio active plant sterol such as stigmasterol and gamma-sitosterol possesses potent Nootropic, antiinflammatory, antioxidant, hypoglycemic and anti-cancer activity.

Keywords: Ipomoea aquatica Forsk; Convolvulaceae; Stigmasterol;Gamma-sitosterol;Gas chromatography.